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Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2

All arthropods periodically molt to replace their exoskeleton (cuticle). Immediately after shedding the old cuticle, the neurohormone bursicon causes the hardening and darkening of the new cuticle. Here we show that bursicon, to our knowledge the first heterodimeric cystine knot hormone found in ins...

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Autori principali: Luo, Ching-Wei, Dewey, Elizabeth M., Sudo, Satoko, Ewer, John, Hsu, Sheau Yu, Honegger, Hans-Willi, Hsueh, Aaron J. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC549504/
https://ncbi.nlm.nih.gov/pubmed/15703293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409916102
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