Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2

All arthropods periodically molt to replace their exoskeleton (cuticle). Immediately after shedding the old cuticle, the neurohormone bursicon causes the hardening and darkening of the new cuticle. Here we show that bursicon, to our knowledge the first heterodimeric cystine knot hormone found in ins...

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Detalles Bibliográficos
Autores principales: Luo, Ching-Wei, Dewey, Elizabeth M., Sudo, Satoko, Ewer, John, Hsu, Sheau Yu, Honegger, Hans-Willi, Hsueh, Aaron J. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC549504/
https://ncbi.nlm.nih.gov/pubmed/15703293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409916102
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