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Membrane Tethered Bursicon Constructs as Heterodimeric Modulators of the Drosophila G Protein–Coupled Receptor Rickets
The study of complex heterodimeric peptide ligands has been hampered by a paucity of pharmacological tools. To facilitate such investigations, we have explored the utility of membrane tethered ligands (MTLs). Feasibility of this recombinant approach was explored with a focus on Drosophila bursicon,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608437/ https://ncbi.nlm.nih.gov/pubmed/23340494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.081570 |
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