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Membrane Tethered Bursicon Constructs as Heterodimeric Modulators of the Drosophila G Protein–Coupled Receptor Rickets

The study of complex heterodimeric peptide ligands has been hampered by a paucity of pharmacological tools. To facilitate such investigations, we have explored the utility of membrane tethered ligands (MTLs). Feasibility of this recombinant approach was explored with a focus on Drosophila bursicon,...

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Библиографические подробности
Главные авторы: Harwood, Benjamin N., Fortin, Jean-Philippe, Gao, Kevin, Chen, Ci, Beinborn, Martin, Kopin, Alan S.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608437/
https://ncbi.nlm.nih.gov/pubmed/23340494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.081570
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