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Discovery of Dual-Action Membrane-Anchored Modulators of Incretin Receptors
BACKGROUND: The glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide-1 (GLP-1) receptors are considered complementary therapeutic targets for type 2 diabetes. Using recombinant membrane-tethered ligand (MTL) technology, the present study focused on defining optimized modu...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173463/ https://ncbi.nlm.nih.gov/pubmed/21935440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024693 |
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