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Chronic Alcohol Exposure Differentially Alters One-Carbon Metabolism in Rat Liver and Brain

BACKGROUND: Epigenetic mechanisms such as DNA methylation play an important role in regulating the pathophysiology of alcoholism. Chronic alcohol exposure leads to behavioral changes as well as decreased expression of genes associated with synaptic plasticity. In the liver, it has been documented th...

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Pubblicato in:Alcohol Clin Exp Res
Autori principali: Auta, James, Zhang, Huaibo, Pandey, Subhash C., Guidotti, Alessandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494979/
https://ncbi.nlm.nih.gov/pubmed/28369960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13382
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