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Chronic Alcohol Exposure Differentially Alters One-Carbon Metabolism in Rat Liver and Brain

BACKGROUND: Epigenetic mechanisms such as DNA methylation play an important role in regulating the pathophysiology of alcoholism. Chronic alcohol exposure leads to behavioral changes as well as decreased expression of genes associated with synaptic plasticity. In the liver, it has been documented th...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Auta, James, Zhang, Huaibo, Pandey, Subhash C., Guidotti, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494979/
https://ncbi.nlm.nih.gov/pubmed/28369960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13382
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