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Haploinsufficient tumor suppressor genes

Haploinsufficiency of tumor suppressor genes (TSGs) indicates that the reduced levels of proteins in cells that lack one allele of the genomic locus results in the inability of the cell to execute normal cellular functions contributing to tumor development. Representative cases of haploinsufficient...

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Detalles Bibliográficos
Publicado en:Adv Med Biol
Main Authors: Inoue, Kazushi, Fry, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494974/
https://ncbi.nlm.nih.gov/pubmed/28680740
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