Mutant p53 proteins bind DNA in a DNA structure-selective mode

Despite the loss of sequence-specific DNA binding, mutant p53 (mutp53) proteins can induce or repress transcription of mutp53-specific target genes. To date, the molecular basis for transcriptional modulation by mutp53 is not understood, but increasing evidence points to the possibility that specifi...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Göhler, Thomas, Jäger, Stefan, Warnecke, Gabriele, Yasuda, Hideyo, Kim, Ella, Deppert, Wolfgang
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
Subjects:
Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549414/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15722483/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gki252
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items