Discrimination of DNA binding sites by mutant p53 proteins.

Critical determinants of DNA recognition by p53 have been identified by a molecular genetic approach. The wild-type human p53 fragment containing amino acids 71 to 330 (p53(71-330)) was used for in vitro DNA binding assays, and full-length human p53 was used for transactivation assays with Saccharom...

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Bibliographic Details
Main Authors: Thukral, S K, Lu, Y, Blain, G C, Harvey, T S, Jacobsen, V L
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC230767/
https://ncbi.nlm.nih.gov/pubmed/7651437
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