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A deterministic method for estimating free energy genetic network landscapes with applications to cell commitment and reprogramming paths

Depicting developmental processes as movements in free energy genetic landscapes is an illustrative tool. However, exploring such landscapes to obtain quantitative or even qualitative predictions is hampered by the lack of free energy functions corresponding to the biochemical Michaelis–Menten or Hi...

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Détails bibliographiques
Publié dans:R Soc Open Sci
Auteurs principaux: Olariu, Victor, Manesso, Erica, Peterson, Carsten
Format: Artigo
Langue:Inglês
Publié: The Royal Society Publishing 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493897/
https://ncbi.nlm.nih.gov/pubmed/28680655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.160765
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