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A deterministic method for estimating free energy genetic network landscapes with applications to cell commitment and reprogramming paths

Depicting developmental processes as movements in free energy genetic landscapes is an illustrative tool. However, exploring such landscapes to obtain quantitative or even qualitative predictions is hampered by the lack of free energy functions corresponding to the biochemical Michaelis–Menten or Hi...

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Detalhes bibliográficos
Publicado no:R Soc Open Sci
Main Authors: Olariu, Victor, Manesso, Erica, Peterson, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493897/
https://ncbi.nlm.nih.gov/pubmed/28680655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.160765
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