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Broad distributions of transition-path times are fingerprints of multidimensionality of the underlying free energy landscapes

Recent single-molecule experiments have observed transition paths, i.e., brief events where molecules (particularly biomolecules) are caught in the act of surmounting activation barriers. Such measurements offer unprecedented mechanistic insights into the dynamics of biomolecular folding and binding...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Satija, Rohit, Berezhkovskii, Alexander M., Makarov, Dmitrii E.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959536/
https://ncbi.nlm.nih.gov/pubmed/33087575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008307117
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