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Broad distributions of transition-path times are fingerprints of multidimensionality of the underlying free energy landscapes
Recent single-molecule experiments have observed transition paths, i.e., brief events where molecules (particularly biomolecules) are caught in the act of surmounting activation barriers. Such measurements offer unprecedented mechanistic insights into the dynamics of biomolecular folding and binding...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7959536/ https://ncbi.nlm.nih.gov/pubmed/33087575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008307117 |
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