The BRCA2-Interacting Protein BCCIP Functions in RAD51 and BRCA2 Focus Formation and Homologous Recombinational Repair

Homologous recombinational repair (HRR) of DNA damage is critical for maintaining genome stability and tumor suppression. RAD51 and BRCA2 colocalization in nuclear foci is a hallmark of HRR. BRCA2 has important roles in RAD51 focus formation and HRR of DNA double-strand breaks (DSBs). We previously...

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Autors principals: Lu, Huimei, Guo, Xu, Meng, Xiangbing, Liu, Jingmei, Allen, Chris, Wray, Justin, Nickoloff, Jac A., Shen, Zhiyuan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Chromosome Structure and Dynamics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549367/
https://ncbi.nlm.nih.gov/pubmed/15713648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1949-1957.2005
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