The BRCA2-Interacting Protein BCCIP Functions in RAD51 and BRCA2 Focus Formation and Homologous Recombinational Repair

Homologous recombinational repair (HRR) of DNA damage is critical for maintaining genome stability and tumor suppression. RAD51 and BRCA2 colocalization in nuclear foci is a hallmark of HRR. BRCA2 has important roles in RAD51 focus formation and HRR of DNA double-strand breaks (DSBs). We previously...

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Publicado en:Mol Cell Biol
Autores principales: Lu, Huimei, Guo, Xu, Meng, Xiangbing, Liu, Jingmei, Allen, Chris, Wray, Justin, Nickoloff, Jac A., Shen, Zhiyuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2005
Materias:
Chromosome Structure and Dynamics
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.5.1949-1957.2005
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