The BRCA2-Interacting Protein BCCIP Functions in RAD51 and BRCA2 Focus Formation and Homologous Recombinational Repair

Homologous recombinational repair (HRR) of DNA damage is critical for maintaining genome stability and tumor suppression. RAD51 and BRCA2 colocalization in nuclear foci is a hallmark of HRR. BRCA2 has important roles in RAD51 focus formation and HRR of DNA double-strand breaks (DSBs). We previously...

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Bibliografiske detaljer
Main Authors: Lu, Huimei, Guo, Xu, Meng, Xiangbing, Liu, Jingmei, Allen, Chris, Wray, Justin, Nickoloff, Jac A., Shen, Zhiyuan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Chromosome Structure and Dynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549367/
https://ncbi.nlm.nih.gov/pubmed/15713648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1949-1957.2005
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