The BRCA2-Interacting Protein BCCIP Functions in RAD51 and BRCA2 Focus Formation and Homologous Recombinational Repair

Homologous recombinational repair (HRR) of DNA damage is critical for maintaining genome stability and tumor suppression. RAD51 and BRCA2 colocalization in nuclear foci is a hallmark of HRR. BRCA2 has important roles in RAD51 focus formation and HRR of DNA double-strand breaks (DSBs). We previously...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Lu, Huimei, Guo, Xu, Meng, Xiangbing, Liu, Jingmei, Allen, Chris, Wray, Justin, Nickoloff, Jac A., Shen, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.5.1949-1957.2005
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