The BRCA2-Interacting Protein BCCIP Functions in RAD51 and BRCA2 Focus Formation and Homologous Recombinational Repair

Homologous recombinational repair (HRR) of DNA damage is critical for maintaining genome stability and tumor suppression. RAD51 and BRCA2 colocalization in nuclear foci is a hallmark of HRR. BRCA2 has important roles in RAD51 focus formation and HRR of DNA double-strand breaks (DSBs). We previously...

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Hlavní autoři: Lu, Huimei, Guo, Xu, Meng, Xiangbing, Liu, Jingmei, Allen, Chris, Wray, Justin, Nickoloff, Jac A., Shen, Zhiyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Chromosome Structure and Dynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC549367/
https://ncbi.nlm.nih.gov/pubmed/15713648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1949-1957.2005
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