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E2F1-regulated long non-coding RNA RAD51-AS1 promotes cell cycle progression, inhibits apoptosis and predicts poor prognosis in epithelial ovarian cancer

Long non-coding RNA RAD51 antisense RNA 1 (RAD51-AS1, also known as TODRA) has been shown to be down-regulated by E2F1, a key cell cycle and apoptosis regulator, in breast cancer. Little is known regarding the role of RAD51-AS1 in disease. Here, we investigate the role of RAD51-AS1 in epithelial ova...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Zhang, Xiaodan, Liu, Guoping, Qiu, Junjun, Zhang, Ning, Ding, Jingxin, Hua, Keqin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493660/
https://ncbi.nlm.nih.gov/pubmed/28667302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04736-z
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