PTOV1 Enables the Nuclear Translocation and Mitogenic Activity of Flotillin-1, a Major Protein of Lipid Rafts

PTOV1 is a mitogenic protein that shuttles between the nucleus and the cytoplasm in a cell cycle-dependent manner. It consists of two homologous domains arranged in tandem that constitute a new class of protein modules. We show here that PTOV1 interacts with the lipid raft protein flotillin-1, with...

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Detalhes bibliográficos
Main Authors: Santamaría, Anna, Castellanos, Elisabeth, Gómez, Valentí, Benedit, Patricia, Renau-Piqueras, Jaime, Morote, Juan, Reventós, Jaume, Thomson, Timothy M., Paciucci, Rosanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549350/
https://ncbi.nlm.nih.gov/pubmed/15713644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1900-1911.2005
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