Regulation of Aurora B Kinase by the Lipid Raft Protein Flotillin-1

The lipid raft protein Flotillin-1 was previously shown to be required for cell proliferation. Here we show that it is critical for the maintenance of the levels of the mitotic regulator Aurora B. Knockdown of Flotillin-1 induced aberrant mitotic events similar to those produced by Aurora B depletio...

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Autores principales: Gómez, Valentí, Sesé, Marta, Santamaría, Anna, Martínez, Juan D., Castellanos, Elisabet, Soler, Marta, Thomson, Timothy M., Paciucci, Rosanna
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898292/
https://ncbi.nlm.nih.gov/pubmed/20430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.130591
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