Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression

BACKGROUND: PTOV1 is an adaptor protein with functions in diverse processes, including gene transcription and protein translation, whose overexpression is associated with a higher proliferation index and tumor grade in prostate cancer (PC) and other neoplasms. Here we report its interaction with the...

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Detalhes bibliográficos
Main Authors: Alaña, Lide, Sesé, Marta, Cánovas, Verónica, Punyal, Yolanda, Fernández, Yolanda, Abasolo, Ibane, de Torres, Inés, Ruiz, Cristina, Espinosa, Lluís, Bigas, Anna, y Cajal, Santiago Ramón, Fernández, Pedro L, Serras, Florenci, Corominas, Montserrat, Thomson, Timothy M, Paciucci, Rosanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021398/
https://ncbi.nlm.nih.gov/pubmed/24684754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-74
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