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Delivery of gene targeting siRNAs to breast cancer cells using a multifunctional peptide complex that promotes both targeted delivery and endosomal release

RNA interference has been used to dissect the importance of individual gene products in various human disease processes, including cancer. Small-interfering RNA, or siRNA, is one of the tools utilized in this regard, but specially-designed delivery agents are required to allow the siRNA to gain opti...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Bjorge, Jeffrey D., Pang, Andy, Fujita, Donald J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493434/
https://ncbi.nlm.nih.gov/pubmed/28666009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180578
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