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Peptide-Functionalized Nanogels for Targeted siRNA Delivery

A major bottleneck in the development of siRNA therapies is their delivery to the desired cell type or tissue, followed by effective passage across the cell membrane with subsequent silencing of the targeted mRNA. To address this problem, we describe the synthesis of core/shell hydrogel nanoparticle...

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Detalhes bibliográficos
Main Authors: Blackburn, William H., Dickerson, Erin B., Smith, Michael H., McDonald, John F., Lyon, L. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765502/
https://ncbi.nlm.nih.gov/pubmed/19341276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800547c
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