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Chemosensitization of cancer cells by siRNA using targeted nanogel delivery

BACKGROUND: Chemoresistance is a major obstacle in cancer treatment. Targeted therapies that enhance cancer cell sensitivity to chemotherapeutic agents have the potential to increase drug efficacy while reducing toxic effects on untargeted cells. Targeted cancer therapy by RNA interference (RNAi) is...

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Detalhes bibliográficos
Main Authors: Dickerson, Erin B, Blackburn, William H, Smith, Michael H, Kapa, Laura B, Lyon, L Andrew, McDonald, John F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820460/
https://ncbi.nlm.nih.gov/pubmed/20064265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-10
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