Role for Hsp70 Chaperone in Saccharomyces cerevisiae Prion Seed Replication

The Saccharomyces cerevisiae [PSI(+)] prion is a misfolded form of Sup35p that propagates as self-replicating cytoplasmic aggregates. Replication is believed to occur through breakage of transmissible [PSI(+)] prion particles, or seeds, into more numerous pieces. In [PSI(+)] cells, large Sup35p aggr...

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Hlavní autoři: Song, Youtao, Wu, Yue-xuan, Jung, Giman, Tutar, Yusuf, Eisenberg, Evan, Greene, Lois E., Masison, Daniel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC549339/
https://ncbi.nlm.nih.gov/pubmed/15701791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.4.2.289-297.2005
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