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Primate Chaperones Hsc70 (Constitutive) and Hsp70 (Induced) Differ Functionally in Supporting Growth and Prion Propagation in Saccharomyces cerevisiae
Hsp70's are highly conserved essential protein chaperones that assist protein folding and prevent protein aggregation. They have modular structures consisting of ATPase, substrate-binding, and C-terminal domains. Substrate binding and release is regulated by ATP hydrolysis and nucleotide exchan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456249/ https://ncbi.nlm.nih.gov/pubmed/16299395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.048926 |
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