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Hsp70 Chaperones as Modulators of Prion Life Cycle: Novel Effects of Ssa and Ssb on the Saccharomyces cerevisiae Prion [PSI(+)]
[PSI(+)] is a prion isoform of the yeast release factor Sup35. In some assays, the cytosolic chaperones Ssa1 and Ssb1/2 of the Hsp70 family were previously shown to exhibit “pro-[PSI(+)]” and “anti-[PSI(+)]” effects, respectively. Here, it is demonstrated for the first time that excess Ssa1 increase...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449557/ https://ncbi.nlm.nih.gov/pubmed/15545639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.037168 |
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