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Propagation of Saccharomyces cerevisiae [PSI(+)] Prion Is Impaired by Factors That Regulate Hsp70 Substrate Binding

The Saccharomyces cerevisiae [PSI(+)] prion is believed to be a self-propagating cytoplasmic amyloid. Earlier characterization of HSP70 (SSA1) mutations suggested that [PSI(+)] propagation is impaired by alterations that enhance Ssa1p's substrate binding. This impairment is overcome by second-s...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Jones, Gary, Song, Youtao, Chung, Seyung, Masison, Daniel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387751/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.3928-3937.2004
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