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Propagation of Saccharomyces cerevisiae [PSI(+)] Prion Is Impaired by Factors That Regulate Hsp70 Substrate Binding
The Saccharomyces cerevisiae [PSI(+)] prion is believed to be a self-propagating cytoplasmic amyloid. Earlier characterization of HSP70 (SSA1) mutations suggested that [PSI(+)] propagation is impaired by alterations that enhance Ssa1p's substrate binding. This impairment is overcome by second-s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387751/ https://ncbi.nlm.nih.gov/pubmed/15082786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3928-3937.2004 |
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