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A Silenced Plasmodium falciparum var Promoter Can Be Activated In Vivo through Spontaneous Deletion of a Silencing Element in the Intron
Introns of Plasmodium falciparum var genes act as transcriptional silencing elements that help control antigenic variations. In transfected episomes, intron silencing of a drug-selectable marker under var promoter control is reversed by the spontaneous deletion of key intron regions. The resulting p...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549332/ https://ncbi.nlm.nih.gov/pubmed/15701812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.4.2.490-492.2005 |
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