Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First- and Second-Line Abiraterone and Enzalutamide

PURPOSE: We reported previously that the detection of androgen receptor splice variant-7 (AR-V7) mRNA in circulating tumor cells (CTCs) correlated with poor outcomes from the use of abiraterone and enzalutamide in patients with castration-resistant prostate cancer (CRPC). Here, we expanded our cohor...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: Antonarakis, Emmanuel S., Lu, Changxue, Luber, Brandon, Wang, Hao, Chen, Yan, Zhu, Yezi, Silberstein, John L., Taylor, Maritza N., Maughan, Benjamin L., Denmeade, Samuel R., Pienta, Kenneth J., Paller, Channing J., Carducci, Michael A., Eisenberger, Mario A., Luo, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493048/
https://ncbi.nlm.nih.gov/pubmed/28384066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.70.1961
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