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Applications of pHLIP Technology for Cancer Imaging and Therapy

Acidity is a biomarker of cancer that is not subject to the blunting clonal selection effects that reduce the efficacy of other biomarker technologies, like antibody targeting. The pH (Low) Insertion Peptides (pHLIPs) provide new opportunities for targeting acidic tissues. Through the physical mecha...

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Detalles Bibliográficos
Publicado en:Trends Biotechnol
Main Authors: Wyatt, Linden C., Lewis, Jason S., Andreev, Oleg A., Reshetnyak, Yana K., Engelman, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492987/
https://ncbi.nlm.nih.gov/pubmed/28438340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2017.03.014
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