In Vitro Activity of Structurally Diverse Nucleoside Analogs against Human Immunodeficiency Virus Type 1 with the K65R Mutation in Reverse Transcriptase

Human immunodeficiency virus type 1 (HIV-1) with a lysine-to-arginine substitution at codon 65 (HIV-1(65R)) of reverse transcriptase (RT) can rapidly emerge in patients being treated with specific combinations of nucleoside analog RT inhibitors (NRTIs). A better understanding of the activity of appr...

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Detalhes bibliográficos
Main Authors: Parikh, Urvi M., Koontz, Dianna L., Chu, Chung K., Schinazi, Raymond F., Mellors, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549267/
https://ncbi.nlm.nih.gov/pubmed/15728915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.1139-1144.2005
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