Rifampin-Resistant RNA Polymerase Mutants of Chlamydia trachomatis Remain Susceptible to the Ansamycin Rifalazil

Stable, homotypic mutants of Chlamydia trachomatis for which MICs of rifampin and rifalazil are elevated were isolated by serial passage at sub-MIC concentrations of these compounds. An alternative approach, in which Chlamydia cells were incubated and subsequently passaged three times, all in the pr...

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Bibliographic Details
Main Authors: Suchland, Robert J., Bourillon, Agnès, Denamur, Erick, Stamm, Walter E., Rothstein, David M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC549232/
https://ncbi.nlm.nih.gov/pubmed/15728912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.1120-1126.2005
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