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Rifampin-Resistant RNA Polymerase Mutants of Chlamydia trachomatis Remain Susceptible to the Ansamycin Rifalazil

Stable, homotypic mutants of Chlamydia trachomatis for which MICs of rifampin and rifalazil are elevated were isolated by serial passage at sub-MIC concentrations of these compounds. An alternative approach, in which Chlamydia cells were incubated and subsequently passaged three times, all in the pr...

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Detalles Bibliográficos
Main Authors: Suchland, Robert J., Bourillon, Agnès, Denamur, Erick, Stamm, Walter E., Rothstein, David M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC549232/
https://ncbi.nlm.nih.gov/pubmed/15728912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.1120-1126.2005
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