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New targets for therapy in breast cancer: Mammalian target of rapamycin (mTOR) antagonists
Mammalian target of rapamycin (mTOR) is a serine-threonine kinase member of the cellular phosphatidylinositol 3-kinase (PI3K) pathway, which is involved in multiple biologic functions such as transcriptional and translational control. mTOR is a downstream mediator in the PI3K/Akt signaling pathway a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549184/ https://ncbi.nlm.nih.gov/pubmed/15318929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr927 |
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