The FOXO3/PGC-1β signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma

In 95% of patients with pancreatic ductal adenocarcinoma, recurrence is observed following chemotherapy. Findings from several studies have indicated that cancer stem cells (CSCs) are resistant to anticancer agents and may be involved in cancer recurrence and metastasis. The CD44 protein is a major...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Kumazoe, Motofumi, Takai, Mika, Hiroi, Shun, Takeuchi, Chieri, Kadomatsu, Mai, Nojiri, Takashi, Onda, Hiroaki, Bae, Jaehoon, Huang, Yuhui, Takamatsu, Kanako, Yamashita, Shuya, Kangawa, Kenji, Tachibana, Hirofumi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Molecular Bases of Disease
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491768/
https://ncbi.nlm.nih.gov/pubmed/28507102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772111
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