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Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells

INTRODUCTION: Cyclin E, a G(1 )cyclin essential for G(1)–S phase transition, is known to have a profound effect on tumorigenesis. Elevated levels of cyclin E have been associated with breast cancer, and chromosomal instability observed in breast cancer is suggested to be associated with constitutive...

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Pubblicato in:Breast Cancer Res
Autori principali: Willmarth, Nicole E, Albertson, Donna G, Ethier, Stephen P
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15318934/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr900
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