Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells
INTRODUCTION: Cyclin E, a G(1 )cyclin essential for G(1)–S phase transition, is known to have a profound effect on tumorigenesis. Elevated levels of cyclin E have been associated with breast cancer, and chromosomal instability observed in breast cancer is suggested to be associated with constitutive...
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| Publicat a: | Breast Cancer Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15318934/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr900 |
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