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Sestrin2 Suppresses Classically Activated Macrophages-Mediated Inflammatory Response in Myocardial Infarction through Inhibition of mTORC1 Signaling

Myocardial infarction (MI) triggers an intense inflammatory response that is essential for dead tissue clearance but also detrimental to cardiac repair. Macrophages are active and critical players in the inflammatory response after MI. Understanding the molecular mechanisms by which macrophage-media...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yang, Keping, Xu, Chenhong, Zhang, Yunfeng, He, Shaolin, Li, Dazhu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491632/
https://ncbi.nlm.nih.gov/pubmed/28713369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00728
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