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Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption
Sepsis, during which the intestinal epithelial barrier is frequently disrupted, remains a challenging and life-threatening problem in clinical practice. The P2X7 receptor (P2X7R) is a non-selective adenosine triphosphate-gated cation channel present in macrophages that is involved in inflammatory re...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491531/ https://ncbi.nlm.nih.gov/pubmed/28663567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04231-5 |
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