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Modeling and optimization of fermentation variables for enhanced production of lactase by isolated Bacillus subtilis strain VUVD001 using artificial neural networking and response surface methodology

Modeling and optimization were performed to enhance production of lactase through submerged fermentation by Bacillus subtilis VUVD001 using artificial neural networks (ANN) and response surface methodology (RSM). The effect of process parameters namely temperature (°C), pH, and incubation time (h) a...

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Publicado en:3 Biotech
Main Authors: Venkateswarulu, T. C., Prabhakar, K. Vidya, Kumar, R. Bharath, Krupanidhi, S.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491433/
https://ncbi.nlm.nih.gov/pubmed/28664372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-017-0802-x
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