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Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations
Ultrasensitive response motifs, capable of converting graded stimuli into binary responses, are well-conserved in signal transduction networks. Although it has been shown that a cascade arrangement of multiple ultrasensitive modules can enhance the system’s ultrasensitivity, how a given combination...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491127/ https://ncbi.nlm.nih.gov/pubmed/28662096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180083 |
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