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Intratumoural production of TNFα by bacteria mediates cancer therapy

Systemic administration of the highly potent anticancer therapeutic, tumour necrosis factor alpha (TNFα) induces high levels of toxicity and is responsible for serious side effects. Consequently, tumour targeting is required in order to confine this toxicity within the locality of the tumour. Bacter...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Murphy, Carola, Rettedal, Elizabeth, Lehouritis, Panos, Devoy, Ciarán, Tangney, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491124/
https://ncbi.nlm.nih.gov/pubmed/28662099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180034
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