Intratumoural production of TNFα by bacteria mediates cancer therapy

Systemic administration of the highly potent anticancer therapeutic, tumour necrosis factor alpha (TNFα) induces high levels of toxicity and is responsible for serious side effects. Consequently, tumour targeting is required in order to confine this toxicity within the locality of the tumour. Bacter...

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Udgivet i:PLoS One
Main Authors: Murphy, Carola, Rettedal, Elizabeth, Lehouritis, Panos, Devoy, Ciarán, Tangney, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491124/
https://ncbi.nlm.nih.gov/pubmed/28662099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180034
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