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LSD1 Substrate Binding and Gene Expression Are Affected by HDAC1-Mediated Deacetylation
Lysine Specific Demethylase 1 (LSD1) catalyzes the demethylation of histone 3 to regulate gene expression. With a fundamental role in gene regulation, LSD1 is involved in multiple cellular processes, including embryonic development, cell proliferation, and metastasis. Significantly, LSD1 is overexpr...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490840/ https://ncbi.nlm.nih.gov/pubmed/27977115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00776 |
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