Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is driven by mutations in PKD1 and PKD2 genes. Recent work suggests that epigenetic modulation of gene expression and protein function may play a role in ADPKD pathogenesis. In this study, we identified SMYD2, a SET and MYND domain protein with ly...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Li, Linda Xiaoyan, Fan, Lucy X., Zhou, Julie Xia, Grantham, Jared J., Calvet, James P., Sage, Julien, Li, Xiaogang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490754/
https://ncbi.nlm.nih.gov/pubmed/28604386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90921
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