Dissecting polyclonal vaccine-induced humoral immunity against HIV using Systems Serology

While antibody titers and neutralization are considered the gold standard for the selection of successful vaccines, these parameters are often inadequate predictors of protective immunity. As antibodies mediate an array of extra-neutralizing Fc-functions, when neutralization fails to predict protect...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Chung, Amy W., Kumar, Manu P., Arnold, Kelly B., Yu, Wen Han, Schoen, Matthew K., Dunphy, Laura J., Suscovich, Todd J., Frahm, Nicole, Linde, Caitlyn, Mahan, Alison E., Hoffner, Michelle, Streeck, Hendrik, Ackerman, Margaret E., McElrath, M. Juliana, Schuitemaker, Hanneke, Pau, Maria G., Baden, Lindsey R., Kim, Jerome H., Michael, Nelson L., Barouch, Dan H., Lauffenburger, Douglas A., Alter, Galit
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490491/
https://ncbi.nlm.nih.gov/pubmed/26544943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.027
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