Dissecting polyclonal vaccine-induced humoral immunity against HIV using Systems Serology

While antibody titers and neutralization are considered the gold standard for the selection of successful vaccines, these parameters are often inadequate predictors of protective immunity. As antibodies mediate an array of extra-neutralizing Fc-functions, when neutralization fails to predict protect...

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Pubblicato in:Cell
Autori principali: Chung, Amy W., Kumar, Manu P., Arnold, Kelly B., Yu, Wen Han, Schoen, Matthew K., Dunphy, Laura J., Suscovich, Todd J., Frahm, Nicole, Linde, Caitlyn, Mahan, Alison E., Hoffner, Michelle, Streeck, Hendrik, Ackerman, Margaret E., McElrath, M. Juliana, Schuitemaker, Hanneke, Pau, Maria G., Baden, Lindsey R., Kim, Jerome H., Michael, Nelson L., Barouch, Dan H., Lauffenburger, Douglas A., Alter, Galit
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490491/
https://ncbi.nlm.nih.gov/pubmed/26544943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.027
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