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Lack of Protection following Passive Transfer of Polyclonal Highly Functional Low-Dose Non-Neutralizing Antibodies

Recent immune correlates analysis from the RV144 vaccine trial has renewed interest in the role of non-neutralizing antibodies in mediating protection from infection. While neutralizing antibodies have proven difficult to induce through vaccination, extra-neutralizing antibodies, such as those that...

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Autors principals: Dugast, Anne-Sophie, Chan, Ying, Hoffner, Michelle, Licht, Anna, Nkolola, Joseph, Li, Hualin, Streeck, Hendrik, Suscovich, Todd J., Ghebremichael, Musie, Ackerman, Margaret E., Barouch, Dan H., Alter, Galit
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018276/
https://ncbi.nlm.nih.gov/pubmed/24820481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097229
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