Divergent Antibody Subclass and Specificity Profiles but Not Protective HLA-B Alleles Are Associated with Variable Antibody Effector Function among HIV-1 Controllers

Understanding the coordination between humoral and cellular immune responses may be the key to developing protective vaccines, and because genetic studies of long-term HIV-1 nonprogressors have associated specific HLA-B alleles with spontaneous control of viral replication, this subject group presen...

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Autors principals: Lai, Jennifer I., Licht, Anna F., Dugast, Anne-Sophie, Suscovich, Todd, Choi, Ickwon, Bailey-Kellogg, Chris, Alter, Galit, Ackerman, Margaret E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958053/
https://ncbi.nlm.nih.gov/pubmed/24352471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03130-13
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