Enhanced Phagocytic Activity of HIV-Specific Antibodies Correlates with Natural Production of Immunoglobulins with Skewed Affinity for FcγR2a and FcγR2b

While development of an HIV vaccine that can induce neutralizing antibodies remains a priority, decades of research have proven that this is a daunting task. However, accumulating evidence suggests that antibodies with the capacity to harness innate immunity may provide some protection. While signif...

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Detalhes bibliográficos
Main Authors: Ackerman, Margaret E., Dugast, Anne-Sophie, McAndrew, Elizabeth G., Tsoukas, Stephen, Licht, Anna F., Irvine, Darrell J., Alter, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648186/
https://ncbi.nlm.nih.gov/pubmed/23468489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03403-12
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