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A convergent total synthesis of ouabagenin

A convergent total synthesis of ouabagenin, an aglycon of cardenolide glycoside ouabain, was achieved by assembly of the AB-ring, D-ring and butenolide moieties. The multiply oxygenated cis-decalin structure of the AB-ring was constructed from (R)-perillaldehyde through the Diels–Alder reaction and...

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Publicat a:Chem Sci
Autors principals: Mukai, Ken, Kasuya, Satoshi, Nakagawa, Yuki, Urabe, Daisuke, Inoue, Masayuki
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490423/
https://ncbi.nlm.nih.gov/pubmed/28706702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00212e
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