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Development of a Concise Synthesis of Ouabagenin and Hydroxylated Corticosteroid Analogues

[Image: see text] The natural product ouabagenin is a complex cardiotonic steroid with a highly oxygenated skeleton. This full account describes the development of a concise synthesis of ouabagenin, including the evolution of synthetic strategy to access hydroxylation at the C19 position of a steroi...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Renata, Hans, Zhou, Qianghui, Dünstl, Georg, Felding, Jakob, Merchant, Rohan R., Yeh, Chien-Hung, Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353025/
https://ncbi.nlm.nih.gov/pubmed/25594682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja512022r
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